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for example OncoGen, and University of Cambridge/DIOSynVax are using immunoinformatics-derived peptide sequences of S protein in their vaccine formulations ( Within the DNA vaccine domain, Immunonomic Therapeutics/EpiVax/PharmaJet are leveraging in silico T-cell epitope prediction 72

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Furthermore, a retrospective study of 147 lung cancer patients with MET exon 14 mutations revealed a 17% ORR and a mPFS of just 1.9 months post-immunotherapy [122]

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Competing interests Masahiko Morita, Ph.D

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